Changes in cAMP effector predominance are associated with increased oxytocin receptor expression in twin but not infection-associated or idiopathic preterm labour.

Although there were similar changes in the cAMP/PKA system in other forms of PTL, they were not associated with increases in OTR expression or the mRNA levels of other cAMP/PKA repressed genes suggesting that these changes may not be significant in the onset of CA- or I-PTL.

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