Distribution and prognostic value of left ventricular global longitudinal strain in elderly patients with symptomatic severe aortic stenosis undergoing transcatheter aortic valve replacement.

Discussion The main findings of this study investigating elderly symptomatic patients with severe AS undergoing TAVR are: (1) LVEF was preserved in 60% of the patients despite advanced symptoms in contrast to LVGLS that was abnormal in 75% (> − 18%) and at least moderately decreased (> − 14%) in approximately half of the patients; (2) a highly significant correlation between LVGLS and all-cause mortality was identified; (3) LVGLS > − 14% was identified as an independent predictor of all-cause mortality and patients with a LVGLS > − 14% had reduced long-term survival as compared to patients with LVGLS ≤ − 14%; (4) patients with high gradient AS with preserved LVEF but LVGLS > − 14% had reduced survival as compared to patients with LVGLS ≤ − 14%.

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