The antitumor effect caused by mCD13‐AFR was highly significant, while neither a non‐targeted BcII10‐AFR nor a fusion protein of mCD13 VHH and wt hIFNα2 (which does not bind the mouse IFNAR) had an effect.
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Safe eradication of large established tumors using neovasculature-targeted tumor necrosis factor-based therapies.
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