A soluble activator that favors the ex vivo expansion of CD8+CD27+ T cells.

JCI Insight · 2020 · PMC7710272 · PMID 33208551

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closest p · 1.2× alpha

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trending toward significanceP = 0.06so close (0.05 < p ≤ 0.1)

This level of expansion was significantly greater than with i αCD3 alone (mean: 119-fold, range: 30- to 208-fold) ( P < 0.005) or after stimulation with i αCD3 with s αCD28 (mean: 173-fold; range, 116- to 224-fold) ( P < 0.05), while also trending toward significance compared with stimulation with TACs ( P = 0.06) (mean: 208-fold, range: 141- to 360-fold).

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