Early disruption of nerve mitochondrial and myelin lipid homeostasis in obesity-induced diabetes.

JCI Insight · 2020 · PMC7710310 · PMID 33148881

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At more advanced diabetic stages (2 months), a similar but milder cardiolipin remodeling was observed in the nerves of diabetic mice, including a significant decrease in cardiolipin tri18:2-18:1 (–35%) and an increasing trend in cardiolipin di18:2-18:1-18:0 ( Figure 5B ).

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