Evaluation of the Role of Circulating Tumor Cells and Microsatellite Instability Status in Predicting Outcome of Advanced CRC Patients.

J Pers Med · 2020 · PMC7712177 · PMID 33217974

Europe PMC DOI

hedged sentence

0.0460

closest p · 0.9× alpha

0.0460

boldest claim

The sentences

marginally significantp = 0.046actually significant

The multivariate analysis revealed that age, PS and the presence of CEACAM5 mRNA-positive CTCs (marginally significant) were independent prognostic factors associated with decreased overall survival (HR = 1.4; 95% CI: 1.0–1.9; p = 0.046; HR = 3.3; 95% CI: 2.0–5.6; p < 0.001 and HR = 1.6; 95% CI: 1.0–2.8; p = 0.056; Table 3 ). 4.

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