highly significantp < 0.005
Introduction A non-adjuvanted cysteine peptidase-based vaccine represents a means of alleviating schistosomiasis symptoms and reducing transmission, as it consistently and repeatedly elicits a highly significant ( p < 0.005, p < 0.0001) reduction in challenge Schistosoma mansoni and Schistosoma haematobium burden in mice and hamsters [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 ].