Telomere lengths in women treated for breast cancer show associations with chemotherapy, pain symptoms, and cognitive domain measures: a longitudinal study.

3 Additional File 5 ). At the mid-chemotherapy time-point, a mixed effects model, adjusted for age, showed significant shortening for 8 telomeres [1p ( p = 0.022), 5q ( p = 0.041), 7q ( p = 0.025), 9q ( p = 0.045), 18q ( p = 0.002), 20p ( p = 0.020), 21q ( p = 0.040), and 22p ( p = 0.025)], along with marginal significance values for decreases in length for 12 additional telomeres [6p, 6q, 7p, 8p, 9p, 10q, 13p, 13q, 14q, 17q, 18p, and 22q] (Additional Files 5 and 6 ).

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