Echinacoside Suppresses Amyloidogenesis and Modulates F-actin Remodeling by Targeting the ER Stress Sensor PERK in a Mouse Model of Alzheimer's Disease.

Front Cell Dev Biol · 2020 · PMC7717986 · PMID 33330477

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an increasing trendno p-value reported

Consistent with previous reports ( Preece et al., 2003 ; O’connor et al., 2008 ; Kim et al., 2018 ), the results ( Figure 4C ) showed that there was no significant difference in BACE1 mRNA among the four indicated groups, even though the mRNA level in ECH-treated 2 × Tg-AD mice exhibited an increasing trend compared with vehicle-treated 2 × Tg-AD.

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