Which Factors Affect the Occurrence of Off-Target Effects Caused by the Use of CRISPR/Cas: A Systematic Review in Plants.

Front Plant Sci · 2020 · PMC7719684 · PMID 33329634

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an obvious trendno p-value reported

Conclusion for Hypothesis 3 Based on the available evidence the results do not indicate that the occurrence of off-target effects shows an obvious trend in relation to the GC-content of the protospacer sequence.

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