Loss of p27Kip1 leads to expansion of CD4+ effector memory T cells and accelerates colitis-associated colon cancer in mice with a T cell lineage restricted deletion of Smad4.

Oncoimmunology · 2020 · PMC7722707 · PMID 33329939

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a trend toward significanceno p-value reported

12 , 15–20 Three out the four remaining studies showed a trend toward significance between low p27 Kip1 protein levels and poor disease outcome.

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