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Altogether, the decreased recurrence rates (RR 0.94, 95% CI: 0.87–1.01; 2p=0.08), the distant recurrence rates (0.92, 95% CI: 0.85–0.99; 2p=0.03) and breast cancer mortality (RR 0.91, 95% CI: 0.83–0.99; 2p=0.04) were defined as borderline significant.

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In postmenopausal patients, there were highly significant reductions seen in the recurrence rate (RR 0.86, 95% CI: 0.78–0.94; 2p=0.002), in the distant recurrence rate (RR 0.82, 95% CI: 0.74–0.92; 2p=0.0003), the rate of bone recurrence (RR 0.72, 95% CI: 0.6–0.86; 2p=0.0002) as well as the breast cancer mortality rate (RR 0.82, 95% CI: 0.73–0.93; 2p=0.002).

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