Comprehensive Mapping of Key Regulatory Networks that Drive Oncogene Expression.

We hypothesized that the surprisingly weak effect of these knockouts on APOBEC3B expression, in light of the highly significant identification of NFKB1 and NFKB2 in the in trans CRISPR-Cas9 screen ( Figure S3E ), may be because of functional redundancy between NFKB1 and NFKB2.

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