Barely Significant
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Long-Term Clinical Results of Use of an Anal Fistula Plug for Treatment of Low Trans-Sphincteric Anal Fistulas.

Med Sci Monit · 2020 · PMC7727077 · PMID 33279927

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may be significantno p-value reported
Infection and abscess formation may be significant causes of treatment failure.

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an increasing trendno p-value reported
With the increase in the number of cases and collective surgical experience, the long-term healing rate of anal fistula plugs shows an increasing trend year-by-year ( Figure 2 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.