borderline significantP = 0.08
In the 4 studies with selenium in the antioxidant mix, there was no association with all-cause mortality, but in the 13 trials without selenium, a possible borderline significant increased risk was seen (RR: 1.05, 95% CI: 0.99, 1.12; P = 0.08; I 2 = 0%; Figure 4 ).