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Trends and patterns in the use of opioids among metastatic breast cancer patients.

Sci Rep · 2020 · PMC7729956 · PMID 33303832

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a decreasing trendno p-value reported
There was a decreasing trend in the daily MME and days’ supply of opioid prescriptions over the study period.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.