Modulation of Brain Hyperexcitability: Potential New Therapeutic Approaches in Alzheimer's Disease.

Currently, a large phase 3 study in mild to moderate Alzheimer’s disease is ongoing, as add-on therapy to cholinesterase inhibitors and/or memantine, with the interim analysis results showing a positive trend of efficacy in one of the Masitinib doses tested [ 141 ], ( Table 1 ). 4.

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