Barely Significant
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Membrane-Dependent Binding and Entry Mechanism of Dopamine into Its Receptor.

ACS Chem Neurosci · 2020 · PMC7735663 · PMID 32538079

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an increasing trendno p-value reported
While the profile demonstrates an increasing trend until the ligand reaches the water phase, it features no substantial barrier at the gate of the binding pocket.

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