The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.

Nucleic Acids Res · 2020 · PMC7736791 · PMID 33270897

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may be significantno p-value reported

In this context, the transition from heptameric to hexameric rings may be significant during the loading of Rep proteins onto dsDNA.

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