Clinical stage molecule PT150 is a modulator of glucocorticoid and androgen receptors with antiviral activity against SARS-CoV-2.

Moreover, systemic elevation of circulating cortisol [ 11 ] and virus-induced neuro-inflammation [ 12 ] are now considered possibly significant co-factors in COVID-19 disease severity and progression.

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There was a highly significant SARS-CoV-2 antiviral response with an average EC90 of 5.55 μM (3130 ng/mL).

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