Highly significant necrosis of tumor cells in the ZrC, ZrC@Iri and ZrC@prodrug groups were checked compared to the control, and ZrC@prodrug and ZrC@Iri induced a higher cell apoptosis rate (TUNEL) with lower cell proliferative activities (Ki67) in tumor compared to the control (Figure 4d ), indicating ZrC@prodrug had a similar anti‐tumor effect compared with ZrC@Iri.
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Prodrug-Loaded Zirconium Carbide Nanosheets as a Novel Biophotonic Nanoplatform for Effective Treatment of Cancer.
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