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Interaction of Ras Binding Domain (RBD) by chemotherapeutic zinc oxide nanoparticles: Progress towards RAS pathway protein interference.

PLoS One · 2020 · PMC7744048 · PMID 33326476

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a decreasing trendno p-value reported
As evident from Fig 3B , zinc concentration in the cell culture medium supernatant followed a decreasing trend over time.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.