Bu-Shen-Huo-Xue Decoction Ameliorates Diabetic Nephropathy by Inhibiting Rac1/PAK1/p38MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.

Moreover, the kidney weight/body weight reduced after administration of high dose BSHX decoction for 4 weeks; however, there was no significant difference between the metformin-treated and DN model groups, although a decreasing trend was detected ( Figures 1H ).

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