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The Effect of Switching from Tenofovir Disoproxil Fumarate (TDF) to Tenofovir Alafenamide (TAF) on Liver Enzymes, Glucose, and Lipid Profile.

Drug Des Devel Ther · 2020 · PMC7751319 · PMID 33364747

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of borderline significanceno p-value reported
Statistically significant AST and ALT variations were found in patients negative both for HCV-Ab and HBsAg (−1, IQR=−5–2, P =0.03; −2, IQR=−7–2, P =0.003 respectively), whereas an ALT decrease was of borderline significance in individuals with positive HCV-Ab and/or Hbs-Ag ( Table 2 ).

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