Coefficient of variation as an image-intensity metric for cytoskeleton bundling.

Both skewness and CV successfully detected microtubule bundling during PPB formation, with the skewness and CV values for differences between the images with and without bundling being highly significant, but more so for CV (Mann–Whitney U-test, P = 8.947e−09 for skewness and P = 6.202e−14 for CV; Fig. 3 B, C, Supplemental Fig. 5 B).

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