Progressive external ophthalmoplegia associated with novel MT-TN mutations.

Acta Neurol Scand · 2021 · PMC7756270 · PMID 32869280

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highly significantno p-value reported

Single fiber analysis in both cases showed highly significant differences in mutation load between COX‐deficient and COX‐normal fibers and a high threshold level for COX deficiency.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.