Pathogenic Germline Mutations of DNA Repair Pathway Components in Early-Onset Sporadic Colorectal Polyp and Cancer Patients.

Cancers (Basel) · 2020 · PMC7761471 · PMID 33260537

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an increasing trendno p-value reported

However, although the incidence of colorectal cancer has been on a steady decline in recent decades, the proportion of early-onset CRC defined by diagnosis before 50 years old appears to be on an increasing trend in the US and Europe [ 4 , 5 ].

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