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Elevated Production of Mitochondrial Reactive Oxygen Species via Hyperthermia Enhanced Cytotoxic Effect of Doxorubicin in Human Breast Cancer Cell Lines MDA-MB-453 and MCF-7.

Int J Mol Sci · 2020 · PMC7765207 · PMID 33333736

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a decreasing trendno p-value reported
There was a decreasing trend in MCF-7, although not significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.