The MAD2 knockdown is depicted in Figure 2 and was highly significant in both SKOV-3 and A2780 cells, the SKOV-3 cell was subsequently chosen for microarrays being a MyD88 positive cell line, which had been shown to display both mechanisms of paclitaxel resistance/sensitivity independently. 18.
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The role of the MAD2-TLR4-MyD88 axis in paclitaxel resistance in ovarian cancer.
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