Periodontal pathogens alter the synovial proteome. Periodontal pathogens do not exacerbate macroscopic arthritis but alter the synovial proteome in mice.

Even though macroscopic disease development tended to develop later in mice that were orally inoculated with Pg compared to mice receiving Aa or sham treatment, the p-value resulting from a Breslow test was 0.086, indicating differences in the early phase of arthritis induction which however, did not quite reach significance.

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