Meta-Analysis of Differentially Expressed Genes in the Substantia Nigra in Parkinson's Disease Supports Phenotype-Specific Transcriptome Changes.

Front Neurosci · 2020 · PMC7775392 · PMID 33390883

Europe PMC DOI

hedged sentences

0.0433

closest p · 0.9× alpha

0.0433

boldest claim

The sentences

marginally significantp = 0.0433actually significant

Overrepresentation analyses were marginally significant in the upregulated DEGs (nominal p = 0.0433), with genes enriched in mature microglia but not in aged microglia.

also in 26,082 other papers

highly significantno p-value reported

Enrichment of PD-related genes was highly significant in downregulated DEGs but insignificant in upregulated genes.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.