S100A8/S100A9 cytokine acts as a transcriptional coactivator during breast cellular transformation.

Sci Adv · 2021 · PMC7775746 · PMID 33523865

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantP < 2.2 × 10 −16actually significant

Notably, 67% of annotated cancer genes are associated with S100A8/A9 target genes, in comparison to only 55% of noncancer genes, which is highly significant ( P < 2.2 × 10 −16 ; Fisher’s exact test) with contributions from ONG ( P = 2 × 10 −8 ), TSG ( P = 2 × 10 −14 ), and OncoTSG enrichment ( P = 6 × 10 −6 ).

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