Endothelial Klf2-Foxp1-TGFβ signal mediates the inhibitory effects of simvastatin on maladaptive cardiac remodeling.

Theranostics · 2021 · PMC7778601 · PMID 33408770

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marginally significantno p-value reported

The MRC/HPS study treatment of HF patients with 40 mg simvastatin daily showed a non-significant trend toward lower HF deaths rate due to any cause and a marginally significant reduction in first hospital admission for worsening HF or HF death 36 , 37 .

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