Barely Significant
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Experimental and theoretical rationalization for the base pairing abilities of inosine, guanosine, adenosine, and their corresponding 8-oxo-7,8-dihydropurine, and 8-bromopurine analogues within A-form duplexes of RNA.

Biopolymers · 2020 · PMC7780609 · PMID 33216981

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an unexpected trendno p-value reported
The only values that came in an unexpected trend were those coming upon comparison of 8‐oxoG or 8‐oxoI base pairing with C (entries 3, 5), where the additional H‐bond on 8‐oxoG should result in a lower energy.

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