Circ_ZFR contributes to the paclitaxel resistance and progression of non-small cell lung cancer by upregulating KPNA4 through sponging miR-195-5p.

Cancer Cell Int · 2021 · PMC7788748 · PMID 33407505

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a decreasing trendno p-value reported

Moreover, there was a decreasing trend in miR-195-5p level from normal tissues to PTX-sensitive NSCLC tissues and then to PTX-resistant NSCLC tissues (Fig. 3 f).

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an increasing trendno p-value reported

There was an increasing trend in KPNA4 mRNA and protein levels from normal tissues to PTX-sensitive tumor tissues and then to PTX-resistant tumor tissues (Fig. 5 i, l).

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