Barely Significant
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Acute IL-1RA treatment suppresses the peripheral and central inflammatory response to spinal cord injury.

J Neuroinflammation · 2021 · PMC7788822 · PMID 33407641

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highly significantno p-value reported
With recent papers demonstrating important interactions between migrating neutrophils and components of the CNS immune system [ 35 ], a better understanding of the peripheral effects of IL-1RA treatment is highly significant as it potentially negates the need to circumvent the precarious blood-CNS barrier.

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