Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth.

Oncogene · 2021 · PMC7790754 · PMID 33110234

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highly significantno p-value reported

In the presence of 0.5 mM H 2 O 2 , four of the six tested gRNAs (including OR1J2, LGALS2 , MT1G and mir320C2 ) showed highly significant effects on promoting cell growth ( Fig. 1G ).

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