Transcranial direct current stimulation induces long-term potentiation-like plasticity in the human visual cortex.

Analyzing the P1N1 amplitude range further substantiated the effects by demonstrating an almost significant difference for PVS (−1.6 μV ± 6.6 μV [SD]; p = 0.055, d = −0.24) and significant differences for tDCS (−1.9 μV ± 6.8 μV [SD]; p = 0.026; d = 0.28), as well as for both (1.9 μV ± 7.6 μV [SD]; p = 0.048, d = 0.24) compared no stimulation (3.1 μV ± 6.3 μV [SD]).

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To further examine a proposed overall measure of VEP plasticity 7 , we analyzed the P1N1 peak-to-peak difference, which showed a highly significant increase of 14.2% following PVS ( F = 19.3; p = <0.001; p η2 = 0.343).

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