The efficiency of MK-801 in reducing the incidence of AGS was highly significant 18 h post-injection and lasted up to 4 days in half of the MK-801-treated Grin2a S/S mice ( N = 4).
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Voltage-independent GluN2A-type NMDA receptor Ca<sup>2+</sup> signaling promotes audiogenic seizures, attentional and cognitive deficits in mice.
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