Barely Significant
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Global Burden, Risk Factors, and Trends of Esophageal Cancer: An Analysis of Cancer Registries from 48 Countries.

Cancers (Basel) · 2021 · PMC7795486 · PMID 33466239

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an increasing trendno p-value reported
Although the incidence of esophageal cancer showed an overall decreasing trend, an increasing trend was observed in some countries with high AC/SCC incidence ratios.

also in 63,971 other papers

a decreasing trendno p-value reported
Thirdly, most countries/regions showed a decreasing trend in the incidence and mortality of esophageal cancer in the recent past decade, especially among males and those aged 50 years or older.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.