Barely Significant
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Addition of carboplatin-gemcitabine as second-line neoadjuvant chemotherapy in non-responsive locally advanced breast cancer patients to standard neoadjuvant chemotherapy and evaluation of factors affecting response: a randomized controlled trial.

BMC Cancer · 2021 · PMC7798240 · PMID 33430808

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close to being significantno p-value reported
Smaller primary tumor size was also more prone to achieving response in the total study population; however, difference was close to being significant ( P value 0.065).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.