Patients with reduced kidney function achieved greater proportional risk reductions for MACE (23% reduction) than patients with preserved kidney function (9% reduction), although the difference was of borderline significance (P for heterogeneity between subgroups = 0.053) (Fig. 1 ) [ 33 ].
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Sodium-glucose transporter-2 inhibitors for prevention and treatment of cardiorenal complications of type 2 diabetes.
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