Pretest Symptom Duration and Cycle Threshold Values for Severe Acute Respiratory Syndrome Coronavirus 2 Reverse-Transcription Polymerase Chain Reaction Predict Coronavirus Disease 2019 Mortality.

Categorizing time after symptom onset into <3 days, 4–7 days, 8–14 days, and 15+ days showed odds of death relative to those presenting 8–14 days after symptom onset (group with the lowest odds of death) to be greatest in those presenting <3 days (OR, 3.1; 95% CI, 2.25–4.32) but still increased in those presenting 4–7 days (OR, 1.5; 95% CI, 1.12–2.04), and with a nonsignificant trend to be worse if presenting >14 days (OR, 1.3; 95% CI, 0.85–2.00) ( Figure 3 ).

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