Human soluble ACE2 improves the effect of remdesivir in SARS-CoV-2 infection.

EMBO Mol Med · 2021 · PMC7799356 · PMID 33179852

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highly significantno p-value reported

Strikingly, however, low doses of hrsACE2 doses (5 and 10 μg/ml) showed additive effects in combination with low dose remdesivir, resulting in strong and highly significant reduction of SARS‐CoV‐2 infectivity in Vero E6 cells (Fig 3C ) and kidney organoids (Fig 3D ).

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