borderline significantp = 0.049
The guide point-based selection method showed borderline significant improvement in the accuracy of mean dose against the WH volume-based selection method only for LMCA (p = 0.049) ( Table S3 ). 4 Discussion The purpose of the current study was to develop an automatic method to segment cardiac substructures given a radiotherapy planning CT to support epidemiological studies or clinical trials looking at cardiac disease endpoints after radiotherapy.