Epigenetic targeting of neuropilin-1 prevents bypass signaling in drug-resistant breast cancer.

The core-EMT genes are similarly modulated by several different master regulators of EMT such as snail, twist, goosecoid, stimulation with TGF-β1 and directed depletion of E-cadherin 30 . Using this approach, we also found a highly significant correlation between the core-EMT signature and the AGR DEG list ( Fig. 2d ).

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