Barely Significant
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Activation of proline biosynthesis is critical to maintain glutamate homeostasis during acute methamphetamine exposure.

Sci Rep · 2021 · PMC7809342 · PMID 33446840

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highly significantno p-value reported
Therefore, our studies showing a functional association between glutamate and proline metabolism during METH exposure are highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.