Aberrant development of pancreatic beta cells derived from human iPSCs with FOXA2 deficiency.

Cell Death Dis · 2021 · PMC7817686 · PMID 33473118

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Furthermore, qPCR results showed a highly significant reduction in the expression of the main endocrine TFs, NGN3 , NEUROD1 , and NKX2.2 in the EPs derived from FOXA2 −/− iPSC lines (Fig. 7E ).

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