Unearthing Antibiotic Resistance Associated with Disturbance-Induced Permafrost Thaw in Interior Alaska.

Influence of Phylogeny and Disturbance-Induced Thaw on ARGs Although the abundance of ARGs increased with FPES disturbance levels (UD = 101, SD = 133, MD = 145), we found the number of CARD hits per isolate was highly significant by phylum (Kruskal-Wallis p = 2.8 × 10 −13 ; Figure 3 a) rather than FPES site (Kruskal-Wallis p = 0.083; Figure 3 b).

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We observed a positive trend in the number of resistant isolates with disturbance-induced thaw for ampicillin, chloramphenicol, and erythromycin that was also observed for intermediate resistance to kanamycin and tetracycline ( Figure 2 b). 3.2.

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