To conform to the hypothesis of ribosome accumulation, we measure the changes of transcriptional activity of 45S pre-ribosomal RNA, observing a non-significant increase in cells treated by EVs by qPCR, and almost significant ( p value 0.07) in cells treated with the vesicular fraction of our preparations ( Supplementary Figure 3 ).
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Extracellular Vesicles From Liver Progenitor Cells Downregulates Fibroblast Metabolic Activity and Increase the Expression of Immune-Response Related Molecules.
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